The 11-14-Week Scan: The Diagnosis of Fetal Abnormalities

by ; ;
Format: Hardcover
Pub. Date: 1999-09-15
Publisher(s): Informa Healthc
List Price: $129.65

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Summary

The 11-14-week scan helps to identify a high proportion of fetuses with trisomy 21 and other chromosomal abnormalities, major defects of the heart and great arteries, and a wide range of skeletal dysplasias and genetic syndromes. Other benefits include confirmation that the fetus is alive, accurate dating of the pregnancy, early diagnosis of major fetal defects, and the detection of multiple pregnancies and identification of chorionicity.The 11-14-Week Scan: The Diagnosis of Fetal Abnormalities is a complete, authoritative clinician's textbook on using ultrasound as the main diagnostic tool in the prenatal detection of congenital abnormalities. It provides the basis of learning for the theoretical component of the Certificate of Competence in the 11-14-week scan awarded by The Fetal Medicine Foundation. The book covers early screening for chromosomal abnormalities, implications of increased nuchal translucency in chromosomally normal fetuses, ultrasound diagnosis of fetal abnormalities, determination of chorionicity and implications and management of multiple pregnancies, and multifetal pregnancy reduction.

Table of Contents

Introduction 1(3)
Nuchal translucency and chromosomal defects
3(64)
Calculation of risk for chromosomal defects
8(6)
Nuchal translucency thickness
14(15)
Pranav Pandya
Increased nuchal translucency and other chromosomal defects
29(2)
Crown-rump length in chromosomally abnormal fetuses
31(2)
Fetal heart rate in chromosomally abnormal fetuses
33(3)
Adolfo Liao
Doppler ultrasound findings in chromosomally abnormal fetuses
36(2)
Nuchal translucency and maternal serum biochemistry
38(3)
Maria Brizot
Penelope Noble
Nuchal translucency followed by second-trimester biochemistry
41(2)
Nuchal translucency followed by second- trimester ultrasonography
43(3)
Non-invasive diagnosis using fetal cells from maternal blood
46(4)
Raghad Al-Mufti
Invasive diagnosis of chromosomal defects
50(17)
Increased nuchal translucency with normal karyotype
67(28)
Athena Souka
Victoria Heath
Small series
68(1)
The Fetal Medicine Foundation Project
68(3)
Fetal defects presenting with increased nuchal translucency thickness
71(1)
Consequences of increased nuchal translucency
71(2)
Conditions associated with increased nuchal translucency
73(1)
Cardiac defects
73(3)
Diaphragmatic hernia
76(1)
Exomphalos
77(1)
Achondrogenesis type II
77(1)
Achondroplasia
78(1)
Asphyxiating thoracic dystrophy
78(1)
Beckwith-Wiedemann syndrome
78(1)
Blomstrand osteochondrodysplasia
79(1)
Body stalk anomaly
79(1)
Campomelic dysplasia
80(1)
Ectrodactyly-ectodermal dysplasia-cleft palate (EEC) syndrome
80(1)
Fetal akinesia deformation sequence (FADS)
81(1)
Fryn syndrome
82(1)
GM1-gangliosidosis
82(1)
Hydrolethalus syndrome
82(1)
Jarcho-Levin syndrome
83(1)
Joubert syndrome
84(1)
Meckel-Gruber syndrome
84(1)
Nance-Sweeney syndrome
84(1)
Noonan syndrome
85(1)
Osteogenesis imperfecta type II
85(1)
Perlman syndrome
86(1)
Roberts syndrome
86(1)
Short-rib polydactyly syndrome
86(1)
Smith-Lemli-Opitz syndrome
87(1)
Spinal muscular atrophy type 1 (Werdnig-Hoffmann disease)
87(1)
Thanatophoric dysplasia
87(1)
Trigonocephaly `C' syndrome
88(1)
VACTERL association
88(1)
Zellweger syndrome
88(7)
Pathophysiology of increased nuchal translucency
95(20)
Constantin von Kaisenberg
Jon Hyett
Cardiac dysfunction
95(8)
Venous congestion in the head and neck
103(1)
Alteration in the extracellular matrix
104(4)
Lymphatic vessel hypoplasia
108(2)
Anemia and hypoproteinemia
110(1)
Congenital infection
110(5)
Diagnosis of fetal abnormalities at the 11-14-week scan
115(34)
Normal first-trimester ultrasound findings
115(8)
Harm-Gerd Blaas
Sturla Eik-Nes
Abnormal ultrasound findings
123(1)
Athena Souka
Spyridon Bakalis
Central nervous system defects
123(8)
Cardiac defects
131(3)
Abdominal wall defects
134(3)
Urinary tract defects
137(4)
Skeletal defects
141(8)
Multiple pregnancy
149(38)
Types of multiple pregnancy
149(1)
Incidence and epidemiology
149(1)
Zygosity and chorionicity
150(3)
Miscarriage and perinatal mortality
153(1)
Severe preterm delivery
154(1)
Growth restriction
155(3)
Twin-to-twin transfusion syndrome
158(4)
Monoamniotic twins
162(2)
Death of one fetus in twin pregnancy
164(1)
Structural defects in multiple pregnancy
165(3)
Chromosomal defects in multiple pregnancy
168(6)
Prenatal determination of chorionicity
174(1)
Multifetal pregnancy and embryo reduction
175(12)
Index 187

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