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Summary

Molecular Biology of the Cellis the classic in-depth text reference in cell biology. By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology.Molecular Biology of the Cellsets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clearand concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice.

Table of Contents

Special Features ix
List of Topics
xi
Acknowledgments xxix
A Note to the Reader xxxiii
PART I INTRODUCTION TO THE CELL
Cells and Genomes
3(44)
Cell Chemistry and Biosynthesis
47(82)
Proteins
129(62)
PART II BASIC GENETIC MECHANISMS
DNA and Chromosomes
191(44)
DNA Replication, Repair, and Recombination
235(64)
How Cells Read the Genome: From DNA to Protein
299(76)
Control of Gene Expression
375(94)
PART III METHODS
Manipulating Proteins, DNA, and RNA
469(78)
Visualizing Cells
547(36)
PART IV INTERNAL ORGANIZATION OF THE CELL
Membrane Structure
583(32)
Membrane Transport of Small Molecules and the Electrical Properties of Membranes
615(44)
Intracellular Compartments and Protein Sorting
659(52)
Intracellular Vesicular Traffic
711(56)
Energy Conversion: Mitochondria and Chloroplasts
767(64)
Cell Communication
831(76)
The Cytoskeleton
907(76)
The Cell Cycle and Programmed Cell Death
983(44)
The Mechanics of Cell Division
1027(38)
PART V CELLS IN THEIR SOCIAL CONTEXT
Cell Junctions, Cell Adhesion, and the Extracellular Matrix
1065(62)
Germ Cells and Fertilization
1127(30)
Development of Multicellular Organisms
1157(102)
Histology: The Lives and Deaths of Cells in Tissues
1259(54)
Cancer
1313(50)
The Adaptive Immune System
1363(60)
Pathogens, Infection, and Innate Immunity
1423
Glossary G-1
Index I-1
Tables: The Genetic Code, Amino Acids T-1

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