Textbook of Pharmacoepidemiology
by Strom, Brian L.; Kimmel, Stephen E.Edition: 1st
Format: Hardcover
Pub. Date: 2007-02-05
Publisher(s): WILEY
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Summary
The Textbook of Pharmacoepidemiology provides a streamlined text for evaluating the safety and effectiveness of medicines. It includes a brief introduction to pharmacoepidemiology as well as sections on data sources, methodology and applications. Each chapter includes key points, case studies and essential references. One-step resource to gain understanding of the subject of pharmacoepidemiology at an affordable price Gives a perspective on the subject from academia, pharmaceutical industry and regulatory agencies Designed for students with basic knowledge of epidemiology and public health Includes many case studies to illustrate pharmacoepidemiology in real clinical setting
Author Biography
Brian L. Strom, University of Pennsylvania School of Medicine, USA.
Stephen E. Kimmel, Associate Professor of Medicine and Epidemiology, University of Pennsylvania School of Medicine, USA.
Table of Contents
| List of Contributors | p. ix |
| Preface | p. xiii |
| Acknowledgments | p. xv |
| Acknowledgments from Pharmacoepidemiology, Fourth Edition | p. xvii |
| Introduction to Pharmacoepidemiology | p. 1 |
| What is Pharmacoepidemiology? | p. 3 |
| Study Designs Available for Pharmacoepidemiology Studies | p. 13 |
| Sample Size Considerations for Pharmacoepidemiology Studies | p. 25 |
| Basic Principles of Clinical Pharmacology Relevant to Pharmacoepidemiology Studies | p. 35 |
| When Should One Perform Pharmacoepidemiology Studies? | p. 55 |
| Views from Academia, Industry, and Regulatory Agencies | p. 63 |
| Sources of Pharmacoepidemiology Data | p. 89 |
| Spontaneous Reporting in the United States | p. 91 |
| Global Drug Surveillance: The WHO Programme for International Drug Monitoring | p. 117 |
| Case-Control Surveillance | p. 137 |
| Prescription-Event Monitoring | p. 151 |
| Overview of Automated Databases in Pharmacoepidemiology | p. 167 |
| Examples of Automated Databases | p. 173 |
| Other Approaches to Pharmacoepidemiology Studies | p. 215 |
| How Should One Perform Pharmacoepidemiology Studies? Choosing Among the Available Alternatives | p. 227 |
| Validity of Pharmacoepidemiologic Drug and Diagnosis Data | p. 239 |
| Special Issues in Pharmacoepidemiology Methodology | p. 259 |
| Bias and Confounding in Pharmacoepidemiology | p. 261 |
| Determining Causation from Case Reports | p. 277 |
| Molecular Pharmacoepidemiology | p. 287 |
| Bioethical Issues in Pharmacoepidemiologic Research | p. 301 |
| The Use of Randomized Controlled Trials for Pharmacoepidemiology Studies | p. 311 |
| The Use of Pharmacoepidemiology to Study Beneficial Drug Effects | p. 321 |
| Pharmacoeconomics: Economic Evaluation of Pharmaceuticals | p. 333 |
| Using Quality-of-Life Measurements in Pharmacoepidemiologic Research | p. 345 |
| The Use of Meta-analysis in Pharmacoepidemiology | p. 353 |
| Patient Adherence to Prescribed Drug Dosing Regimens in Ambulatory Pharmacotherapy | p. 367 |
| Novel Approaches to Pharmacoepidemiology Study Design and Statistical Analysis | p. 383 |
| Special Applications of Pharmacoepidemiology | p. 397 |
| Special Applications of Pharmacoepidemiology | p. 399 |
| The Future of Pharmacoepidemiology | p. 447 |
| Sample Size Tables | p. 455 |
| Glossary | p. 473 |
| Index | p. 481 |
| Table of Contents provided by Ingram. All Rights Reserved. |
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